1-Be content savvy, because facilitating a classical process-detached-from-content session encounters too many cultural obstacles.
2-Offer your own opinions and content input with which people can agree or differ, because the cultural variance may be so wide that the groups will not be able to generate meaningful content.
3-Build the small break out working groups very carefully, because too much diversity may make the discussion sterile.
4-Make sure that participants are engaged. If not, stop and work on what`s wrong. It is easy to fall into a pattern of apparent participation in very diverse and stranger groups.